Locker hurt his right foot in the second quarter at the end of an option keeper. He was so hobbled he couldn't connect with Johnson on a handoff on the  next play, and the Jaguars recovered with 6:22 left.
Fitzpatrick replaced Locker, and he threw for 264 yards and two touchdowns. He also ran for a 4-yard TD with 4:15 left trying to rally the Titans. But after the Titans forced the Jaguars to go three and out, Fitzpatrick was sacked by Jaguars cornerback Will Blackmon,Wholesale Nike NFL Shop, who stripped him of the ball and ran it back 21 yards for a 29-20 lead.