Manuel has gone 4-6 as a starter and was finally showing signs of progress after winning his first road game,WBC Jerseys. The game against Miami was to be a chance for Manuel to help Buffalo string together consecutive wins for the first time since Weeks 2 and 3 of 2012.
The Bills will also likely be without top receiver Stevie Johnson, who has been excused to be with his family in California following the unexpected death of the player's mother on Saturday.